Blog entry by Evie Corbin
ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or keep ADHD medications during breastfeeding and pregnancy is challenging for women with the condition. There is a lack of information about how long-term exposure to these medications may affect the fetus.
A recent study published in Molecular Psychiatry shows that children exposed to ADHD medication in utero do not develop neurological developmental disorders like hearing loss or impaired vision seizures, febrile seizures, or IQ impairment. The authors acknowledge that further high-quality studies are needed.
Risk/Benefit Analysis
Women who are pregnant and take Strattera adhd Medication medication should evaluate the benefits of using it versus the risks to the foetus. Doctors don't have the information needed to provide clear recommendations, but they can provide information regarding risks and benefits that help pregnant women make informed choices.
A study published in Molecular Psychiatry found that women who took ADHD medications during early pregnancy did not have an increased risk of fetal heart malformations or major structural birth defects. The researchers used a large, population-based case-control study to assess the risk of major structural birth defects in babies born to mothers who had taken stimulants in the early stages of pregnancy, as well as those who had not. Pediatric cardiologists, clinical geneticists and other experts examined the cases to make sure that the classification was correct and to minimize any bias.
The study conducted by the researchers had some limitations. The researchers were unable in the beginning to distinguish the effects of the medication from the disorder. This makes it difficult for researchers to establish whether the few associations observed between the exposed groups were due to medication use or caused by comorbidities. In addition the researchers did not study the long-term outcomes of offspring.
The study did reveal that infants whose mothers took ADHD medication during pregnancy were at a slightly greater risk of being admitted to the neonatal intensive care unit (NICU) than infants whose mothers had not taken any medication or cut back on their medications prior to or during pregnancy. This was due to central nervous system disorders, and the higher risk of admission did not appear to be influenced by which stimulant medications were taken during pregnancy.
Women who were taking stimulant ADHD medication during pregnancy also had an increased chance of having a caesarean birth or having a child with an low Apgar score (less than 7). These increases did not appear to be influenced by the type of medication that was used during pregnancy.
Researchers suggest that the small risk of using ADHD medications in early pregnancies could be offset by the greater benefits for mother and baby of continuing treatment for the woman's disorder. Physicians should discuss this with their patients and, where possible, assist them in developing strategies to improve their coping abilities that may minimize the impact of her disorder on her daily life and relationships.
Interactions with Medication
Doctors are increasingly confronted with the dilemma of whether to keep treatment or stop it during pregnancy as more women are diagnosed with ADHD. The majority of these decisions are made without clear and authoritative evidence either way, so physicians have to weigh their experience from their own experiences, those of other doctors, and what research suggests on the subject and their own judgments for each individual patient.
Particularly, the issue of potential risks to the baby can be a challenge. The research on this subject is based on observations rather than controlled studies and the results are contradictory. In addition, most studies limit their analysis to live births, which may underestimate the severity of teratogenic effects that could result in abortion or termination of the pregnancy. The study that is discussed in this journal club addresses these shortcomings by looking at data from both live and deceased births.
The conclusion is that while some studies have found an association between ADHD medications and the risk of certain birth defects, others have not found any evidence of a link and the majority of studies demonstrate a neutral or slightly negative effect. In all cases it is imperative to conduct a thorough study of the benefits and risks should be conducted.
It can be challenging, if not impossible for women suffering from ADHD to stop taking their medication. In a recent article in the Archives of Women's Mental Health psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can increase depression, feelings of isolation, and family conflict for patients with natural adhd medication. In addition, a decrease in medication can affect the ability to complete jobs and drive safely which are essential aspects of a normal life for a lot of people with ADHD.
She suggests women who are uncertain about whether or not to stop medication in light of their pregnancy, consider informing family members, friends and colleagues on the condition, its impact on daily functioning, and the advantages of staying on the current treatment regimen. It can also aid in ensuring that the woman feels supported in her struggle with her decision. It is important to note that certain medications can pass through the placenta, so if the patient decides to discontinue her ADHD medication during pregnancy and breastfeeding, she should be aware of the possibility that traces of the medication could be passed on to the baby.
Birth Defects and Risk of
As the use of best adhd medication for adults medications to treat symptoms of attention deficit hyperactivity disorder (ADHD) increases as do concerns about what impact the drugs might have on fetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge regarding this issue. Using two massive data sets researchers were able examine more than 4.3 million pregnancies to determine whether the use of stimulant medications increased the risk of birth defects. Researchers discovered that although the risk overall is low, first-trimester ADHD medication exposure was associated with slightly higher risk of certain heart defects, like ventriculoseptal defect.
The researchers behind the study found no link between early medication use and congenital abnormalities such as facial clefting or club foot. The results are in line with previous studies which showed an insignificant, but small increase in the number of cardiac malformations among women who started taking adhd medication uk for adults medication prior to the time of the birth of their child. The risk grew in the later part of pregnancy, as many women begin to discontinue their medication.
Women who took ADHD medications during the first trimester of pregnancy were also more likely to have caesarean section, low Apgar score after delivery and a baby that required breathing assistance at birth. However the researchers of the study were not able to eliminate selection bias by restricting the study to women who didn't have any other medical conditions that could have contributed to the findings.
Researchers hope their research will inform physicians when they meet pregnant women. The researchers suggest that, while discussing risks and benefits are crucial, the decision about whether to continue or stop medication should be made in light of the severity of each woman's ADHD symptoms and her needs.
The authors also advise that while discontinuing the medications is an alternative, it is not an option that is recommended due to the high rate of depression and other mental health issues among women who are pregnant or recently postpartum. Further, research shows that women who stop taking their medications will have a tough transitioning to life without them after the baby is born.
Nursing
It can be a challenge to become a mom. Women suffering from ADHD may face a lot of challenges when they must manage their symptoms, attend doctor appointments, prepare for the birth of a baby and adjust to a new routine. Many women choose to continue taking their ADHD medication during pregnancy.
The risk for nursing infant is low because the majority of stimulant medication is absorbed through breast milk at a low level. The amount of exposure to medications can vary depending upon the dosage and frequency of administration as well as the time of the day. Additionally, different medications enter the baby's system differently through the gastrointestinal tract and breast milk, and the effect of this on a newborn isn't well known.
Due to the absence of evidence, some doctors may be inclined to discontinue stimulant medication during the pregnancy of a woman. This is a difficult choice for the patient, who must balance the benefit of continuing her medication against the potential dangers to the foetus. In the meantime, until more information is available, doctors should ask all pregnant patients about their experience with ADHD and whether they are planning or taking to take medication during the perinatal time.
Numerous studies have proven that women can continue to take their ADHD medication in a safe manner during pregnancy and while breast-feeding. This has led to more and more patients opt to do this and in consultation with their doctor they have discovered that the benefits of keeping their current medication outweigh any potential risks.
Women who suffer from ADHD who plan to breastfeed should seek the advice of a specialist psychiatrist before becoming pregnant. They should review their medications with their physician and discuss the advantages and disadvantages of continued treatment, including non prescription adhd medication uk-pharmacological management strategies. Psychoeducation should also be offered to help pregnant women suffering from ADHD recognize their symptoms and the root cause, learn about available treatment options and strengthen existing coping strategies. This should be a multidisciplinary approach together with obstetricians, GPs, and psychiatrists. Pregnancy counseling should consist of a discussion of a treatment plan for the mother and the child, as well as monitoring for indicators of deterioration, and, if necessary, adjustments to the medication regime.